Traitement en cours...

XenTech is a Contract Research Organization (CRO) offering tumorgraft-based services in preclinical oncology.

To foster therapeutic development in oncology, XenTech performs preclinical pharmacology studies using one of the world’s largest and best characterized collection of patient-derived primary tumor xenograft models (so-called tumorgrafts) established without intermediary cell culture.

XenTech’s preclinical platform is based on panels of human tumorgrafts with clinically relevant characteristics defined by genomics and chemosensitivity data. This platform allows reliable preclinical validation studies that increase the chances of success of oncology compounds beyond phase 1 development.
Studies conducted at XenTech complete the preclinical screening performed by pharmaceutical companies and contribute to more efficient clinical trial design by:
  • Predicting activity of compounds in specific tumor types
  • Allowing better activity profiling and response marker identification by performing efficacy studies in tumor panels that recapitulate tumor heterogeneity found in clinical populations


  • XenTech offers consulting in preclinical oncology and is rapidly expanding its range of tumor models and technologies, such as non-invasive imaging to monitor orthotopic and metastatic tumor growth and ex vivo clonogenic and organotypic drug screening assays
    [Agendas]
    AACR-NCI-EORTC Symposium
    Molecular targets and cancer therapeutics
    12-16 November, 2011 I San Francisco, CA, USA
    to know more
    AACR 102nd Annual Meeting
    2-6 April, 2011 I Orlando, USA
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    6th Annual Biomarkers Congress
    23-24 February, 2011 I Manchester, UK
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    [News & Press]
    XenTech welcomes a Postdoctoral Research Fellow
    (Marie Curie Fellowship in Cancer Stem Cell Research)
    September 2011
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    Appointment of Truong-An Tran and Ludovic Bourré as Study Directors
    September 2010
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    XenTech expands its breast tumorgraft collection
    October 2010
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    [Publication]
    A preclinical platform of mouse-transplanted human pediatric liver tumors
    Poster - AACR symposium - April 2011
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    Early detection of pro-apoptotic effects
    Poster - EORTC-NCI-AACR symposium - 18 November 2010
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    A new and fast in vitro screen using primary cells
    Poster - EORTC-NCI-AACR symposium - 18 November 2010
    to know more

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