in vitro cell lines
XenTech has developed methods allowing the establishment of in vitro 2D cell lines from PDX models with 83% success rate.
These PDX-derived low passage 2D cell lines show good similarities in drug response in vitro with that of their parental PDX models in vivo.
This in vitro platform helps guiding subsequent in vivo preclinical drug testing in the parental PDX models.
XenTech keeps on expanding its current panel of 40+ PDX-derived cell models to cover a growing variety of tumor types and genotypes from its PDX model collection.
01Available PDX-derived cell lines
XenTech provides clients with reproducible and consistent in vitro assays, expertise in standard or custom assay design and implementation, over 40 cell lines available in-house (custom cell lines may be provided by the client as well).
Assays include short-term Cell proliferation and cytotoxicity (IC50/IC90 determination), MMT (cell metabolic assay) and long-term colony forming assays (CFU).