In Vitro Testing

XenTech offers PDX-derived primary cell cultures to screen drug candidates ex-vivo prior to performing in vivo efficacy studies.

Primary cell culture assay gives a rapid and lower cost evaluation of drug activity in a range a tumors, as well as minimizing the risk
of failure of in vivo assays.

  • 2D primary cultures obtained from freshly explanted tumor PDX
  • No selective pressure (cells cultured for less than 5 passages).
  • 40+ cellular models derived from our PDX panels are available in several indications like Breast, Brain, Colon, Lung, Ovary, Melanoma, and more in development… Contact us for a detailed list.

We perform cell viability : 96-well plate format, 1 PDX model, up to 6 compounds, 10 concentrations/compound or colony assays.