In Vitro Testing

 

 

XenTech offers PDX-derived primary cell cultures to screen drug candidates prior to performing in vivo efficacy studies.

 

Primary cell culture assay gives a rapid and lower cost evaluation of drug activity in a range a tumors, as well as minimizing the risk
of failure of in vivo assays.

 

  • 2D primary cultures obtained from freshly explanted tumor PDX
  • No selective pressure (cells cultured for less than 5 passages).
  • 6 cancer types: Breast (3), Brain (2), Colon (3), Lung (1), Ovary (1), Melanoma (2), and more in development…

We perform cell viability assay: 96-well plate format, 1 PDX model, up to 5 compounds, 10 concentrations/compound.