Category: Publications

Publications

Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification

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Publications

Targeting genome integrity dysfunctions impedes metastatic potency in non-small-cell lung cancer circulating tumor cellderived eXplants

CTC-derived eXplants (CDX) offer systems for mechanistic investigation of CTC metastatic potency and may provide rationale for biology-driven therapeutics.

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Publications

STING protects breast cancer cells from intrinsic and genotoxic-induced DNA instability via a non-canonical, cell-autonomous pathway – Oncogene, Oct.8 2021

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Publications

Paediatric Liver Cancer

A preclinical platform of mouse-transplanted human pediatric liver tumors to evaluate the efficacy of conventional and innovative anticancer therapy

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Publications

Paediatric Liver Cancer

Liver cancer patient-derived xenografts to improve disease management in childhood and adolescence: perspectives and challenges of personalized medicine

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Publications

Paediatric Liver Cancer

A panel of pediatric liver cancer patient-derived xenografts to improve stratification of children with hepatoblastoma

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Publications

2D PDX-derived primary cultures

A new and fast in vitro screen to predict in vivo drug efficacy using cell primary culture from patient derived tumor established xenografts

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Publications

Liver Cancer

Myc Target miRs and Liver Cancer: Small Molecules to Get Myc Sick

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Publications

Breast Cancer

STX140 is efficacious in vitro and in vivo in taxane-resistant breast carcinoma cells

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Publications

Brain Cancer

ASPM-associated stem cell proliferation is involved in malignant progression of gliomas and constitutes an attractive therapeutic target

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